The short version
| Weekly injection | Daily tablet | |
|---|---|---|
| How it's taken | Small subcutaneous injection, once weekly | Dissolvable tablet, once daily |
| Molecule | Semaglutide (GLP-1 receptor agonist) | Same molecule, oral delivery |
| Routine | One weekly moment; easy to forget it's part of your life | Daily habit; no needles, no sharps disposal |
| Travel | Needs modest planning | Drop it in a bag |
| Typical experience | The most-studied format; decades of injectable-peptide practice | Preferred by the needle-averse; adherence depends on daily consistency |
| Agave pricing | From $179/mo | From $209/mo |
What actually matters in the choice
1. Which one will you actually stick with?
Consistency beats format. If a weekly injection sounds like a chore you'll dread, the daily tablet's small ritual may serve you better. If daily anything is where your habits go to die, one appointment with yourself per week wins. Be honest about your own patterns — this single factor outweighs everything else on this page.
2. Needle comfort
The injection uses a very fine, short needle — most patients say it's a non-event within a couple of weeks. But "most patients" isn't everyone. If needle aversion would make you skip doses or avoid starting at all, the tablet exists precisely for you.
3. Cost
At Agave the formats are priced $30/month apart ($179 injection vs. $209 tablet at 52-week rates, both all-inclusive), so cost is a minor factor. Elsewhere, compare carefully: many programs price orals very differently, and cash-pay branded programs commonly run $300–500+/month before extras.
4. Your provider's read on your health picture
Absorption, other medications, digestive history — details from your intake can make a provider recommend one format over the other. That conversation is the point of a real telehealth service.
Can you switch later?
Yes. Format isn't a life sentence — patients switch between tablet and injection with their provider's guidance. Because Agave's pricing is flat and all-inclusive, switching doesn't create surprise costs.
Compare all options on our weight loss page, or see the full pricing table. Both formats are compounded by U.S. state-licensed pharmacies and are not FDA-approved; a licensed provider reviews every intake.